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Lilly and Innovent Biologics Expand Strategic Alliance to Include Immuno-Oncology Bispecific Antibodies in China and Globally

Oct. 11, 2015

Eli Lilly and Innovent Biologics announced on Oct. 11, 2015 that their drug development collaboration would be expanded. Their collaboration is already one of the largest in China between a multi-national and domestic biopharmaceutical company.

According to the agreement, the companies will collaborate to support the development and potential commercialization of up to three anti-PD-1 based bispecific antibodies for cancer treatments over the next decade, both inside and outside of China.

Innovent will now have the rights to develop, manufacture and commercialize these potential cancer treatments for China, subject to a Lilly opt-in right for co-development and commercialization. 

Under the terms of the expanded agreement, Innovent could receive additional milestones totaling more than $1 billion if the products reach certain development, regulatory and sales milestones, both inside and outside of China. Sales royalties and other payments would occur on certain products if commercialized outside China. Further financial terms were not disclosed.

Lilly will create the three preclinical anti-PD-1 based bispecific antibodies using an antibody sequence contributed by Innovent.